🧬 Case-Based Questions

Mendelian Genetics Practice

πŸ“— Case Study 1: Mendel’s Dihybrid Cross
Mendel crossed a pure-breeding pea plant with round yellow seeds (RRYY) with a pure-breeding plant having wrinkled green seeds (rryy). All plants in the F₁ generation showed round yellow seeds. On self-pollination of F₁ plants, four different phenotypes appeared in the Fβ‚‚ generation.
1. What is the genotype of the F₁ generation?
A. RRYY
B. rryy
C. RrYy
D. RRYy
βœ… Answer: C
F₁ receives one allele from each parent β†’ RrYy.
2. Which phenotypic ratio is observed in Fβ‚‚?
A. 3 : 1
B. 1 : 2 : 1
C. 9 : 3 : 3 : 1
D. 1 : 1 : 1 : 1
βœ… Answer: C
Independent assortment produces 9:3:3:1 ratio.
3. Which phenotype appears least frequently?
A. Round yellow
B. Round green
C. Wrinkled yellow
D. Wrinkled green
βœ… Answer: D
Wrinkled green (rryy) occurs once out of 16.
4. Which Mendelian law is proved?
A. Dominance
B. Segregation
C. Independent assortment
D. Linkage
βœ… Answer: C
Genes assort independently.
πŸ“— Case Study 2: Formation of Gametes
A student studies gamete formation in a pea plant with genotype RrYy.
5. How many types of gametes are formed?
A. 1
B. 2
C. 3
D. 4
βœ… Answer: D
Gametes: RY, Ry, rY, ry.
6. Which process causes independent assortment?
A. Fertilization
B. Mitosis
C. Meiosis
D. Cytokinesis
βœ… Answer: C
Occurs during meiosis I.
7. Stage of meiosis for assortment?
A. Prophase I
B. Metaphase I
C. Anaphase II
D. Telophase I
βœ… Answer: B
Random alignment at Metaphase I.
πŸ“— Case Study 3: Dihybrid Test Cross
A heterozygous plant (RrYy) is crossed with rryy.
8. What type of cross?
A. Self
B. Back
C. Test cross
D. Reciprocal
βœ… Answer: C
Cross with homozygous recessive.
9. Expected phenotypic ratio?
A. 3 : 1
B. 9 : 3 : 3 : 1
C. 1 : 2 : 1
D. 1 : 1 : 1 : 1
βœ… Answer: D
Equal gamete contribution.
10. Why is test cross important?
A. Increase variation
B. Identify dominant genes
C. Determine genotype
D. Create hybrids
βœ… Answer: C
Reveals homozygous/heterozygous nature.
πŸ“— Case Study 4: Linked Genes vs Independent Assortment
In an experiment, two traits were observed to be inherited together without forming new combinations.
11. What does this observation indicate?
A. Independent assortment
B. Mutation
C. Gene linkage
D. Polygenic inheritance
βœ… Answer: C
Linked genes do not assort independently.
12. Why does Mendel’s law of independent assortment not apply here?
A. Genes are dominant
B. Genes are recessive
C. Genes are linked
D. Genes mutate
βœ… Answer: C
Linked genes remain together during inheritance.
πŸ“— Case Study 5: Genetic Variation
Dihybrid crosses are important in understanding natural variation in organisms.
13. Which factor increases variation in dihybrid crosses?
A. Mitosis
B. Independent assortment
C. Binary fission
D. Cloning
βœ… Answer: B
Independent assortment creates new combinations.
14. Recombinant phenotypes are formed due to
A. Mutation
B. Independent assortment
C. Dominance
D. Purity of gametes
βœ… Answer: B
Recombinants result from new allele combinations.
15. Which of the following is a recombinant phenotype?
A. Round yellow
B. Wrinkled green
C. Round green
D. None of these
βœ… Answer: C
Round green was absent in parental generation.