Question 1

Genetic disorders are caused due to

Explanation: Genetic disorders result from gene or chromosomal abnormalities.

Question 2

Mendelian disorders are

Question 3

Which of the following is a Mendelian disorder?

Question 4

Sickle cell anaemia is inherited as

Question 5

The mutation responsible for sickle cell anaemia is

Question 6

In sickle cell anaemia, which amino acid is replaced?

Question 7

Phenylketonuria is caused due to deficiency of

Question 8

Phenylketonuria is inherited as

Question 9

Accumulation of phenylalanine affects

Question 10

Huntington’s disease is

Question 11

Huntington’s disease generally appears

Question 12

Haemophilia is a disorder related to

Question 13

Haemophilia is inherited as

Question 14

Haemophilia affects mostly

Question 15

Colour blindness is a

Question 16

Which chromosome carries genes for colour blindness?

Question 17

Chromosomal disorders occur due to

Question 18

Gain or loss of one chromosome is called

Question 19

Down syndrome is caused by

Question 20

The chromosome number in Down syndrome is

Question 21

Turner syndrome is represented by

Question 22

Turner syndrome affects

Question 23

Klinefelter syndrome has the karyotype

Question 24

Klinefelter syndrome results in

Question 25

Cri-du-chat syndrome is due to

Question 26

The characteristic cry in Cri-du-chat syndrome resembles

Question 27

Nondisjunction occurs during

Question 28

Which disorder is caused by nondisjunction?

Question 29

Structural chromosomal abnormalities include

Question 30

Which disorder is X-linked recessive?

Question 31

Why are males more affected in X-linked disorders?

Question 32

Autosomal recessive disorders appear when

Question 33

Which disorder shows delayed onset?

Question 34

A carrier female for haemophilia is

Question 35

The study of genetic disorders helps in

Question 36

Chromosomal disorders do NOT follow

Question 37

Which disorder affects intelligence most severely if untreated?

Question 38

The extra chromosome in Down syndrome is

Question 39

Which genetic disorder affects blood oxygen transport?

Question 40

Turner syndrome individuals are

Question 41

Klinefelter syndrome is characterized by

Question 42

Which disorder is due to monosomy?

Question 43

Which is a sex chromosomal disorder?

Question 44

Which disorder involves abnormal haemoglobin?

Question 45

Phenylketonuria affects metabolism of

Question 46

Which disorder can be managed by diet control?

Question 47

Which disorder affects blood clotting?

Question 48

Which disorder is inherited?

Question 49

Genetic counselling is important for

Question 50

Most Mendelian disorders are caused by